SFR Santé Lyon Est

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CyLE: Cytométrie Lyon-Est
Contacter Cytométrie Lyon-Est
Centre de Recherche en Cancérologie
Bâtiment Cheney B - 3ème étage
28 rue Laennec, 69008 Lyon
Téléphone: 04 78 78 29 12
La plateforme de cytométrie en flux du CRCL est intégrée à la SFR Lyon-Est (CYLE), met à disposition pour l’ensemble de la communauté scientifique, une instrumentation de haute technologie regroupant la cytométrie en flux, la cytométrie à spectre entier (de dernière génération) et le tri cellulaire.

La plateforme est depuis 2020 engagée dans une démarche qualité pour satisfaire un haut niveau d’exigence dans la génération des données.

Les missions de la plateforme sont d’apporter support et expertise aux chercheurs souhaitant développer des projets en cytométrie en flux, du montage du panel à l’analyse des données.

La plateforme de cytométrie collabore étroitement avec la plateforme d’immuno-monitoring PI3 pour le développement de l’analyse translationnelle. Nous partageons ainsi l’expertise dans le montage de panels à haut contenu d’information et l’analyse des jeux de données afin d’optimiser le développement des études transversales conduites par la plateforme P3i.



EQUIPEMENTS

La plateforme de cytométrie dispose d’une large gamme de cytomètres et trieurs multi-couleurs dédiés à la recherche et à l’analyse longitudinale.

Détails des configurations : https://www.crcl.fr/les-plateformes/plateforme-de-cytometrie-en-flux/plateforme-de-cytometrie-en-flux-instruments/

Accès site de réservation : https://sfrsantelyonest.univ-lyon1.fr/resas/cyto/select.php

Fiche de demande de tri : https://framaforms.org/demande-de-tri-cellulaire-1646836904



FORMATIONS

La plateforme de cytométrie propose deux types de formations : formation DiVa (cytométrie en flux) et formation SpectroFlo (Cytométrie à spectre entier).

Formations DiVa : https://www.crcl.fr/agenda/formations-diva/

Formation Spectroflo : https://www.crcl.fr/agenda/test-2/



PRESTATIONS

La plateforme de cytométrie propose des prestations de marquage pour des suivis phénotypiques chez l’homme et la souris, à partir de panels optimisés, autant au niveau technique qu'analytique.



Membres du comité de pilotage de la plateforme :

POURCHET Julie, BIOTA Cathy, BERTOLINO Philippe, CARAMEL Julie, KANIEWSKI Bastien, VALLADEAU Jenny, COSSET Erika, GABUT Mathieu, RUBY Samia, GRINBERG-BLEYER Yenkel, BERTHENET Kévin, HENNINO Anca, JACQUEMETTON Julien, CASCALES Elodie, PLISSONNIER Marie-Laure, LEFORT Sylvain, SOUDJA Saidi, GOLDSCHNEIDER David, PETRILLI Virginie, DURET Cédric, VANBERVLIET Béatrice, BARTOSCH Birke
https://www.crcl.fr/les-plateformes/plateforme-de-cytometrie-en-flux/
Bibliographie
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# article crédits PDF
1 Human myeloid differentiation by BMP4 signaling through the VDR pathway in acute myeloid leukemia
Zylbersztejn F, Byelinska I, Jeanpierre S, Barral L, Geistlich K, Flores-Violante M, Voeltzel T, Paubelle E, Heiblig M, Alcazer V, Le Meur G, Fossard G, Belhabri A, Cruz-Moura I, Hermine O, Lefort S, Maguer-Satta V
Cell Death Discov 2024 10(1): 325
PMID: 39013874 - DOI: 10.1038/s41420-024-02090-4
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2 Modulation of blood T cell polyfunctionality and HVEM/BTLA expression are critical determinants of clinical outcome in anti-PD1-treated metastatic melanoma patients
Dalle S, Verronese E, N'Kodia A, Bardin C, Rodriguez C, Andrieu T, Eberhardt A, Chemin G, Hasan U, Le-Bouar M, Caramel J, Amini-Adle M, Bendriss-Vermare N, Dubois B, Caux C, Ménétrier-Caux C
Oncoimmunology 2024 13(1): 2372118
PMID: 38939518 - DOI: 10.1080/2162402X.2024.2372118
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3 Deep phenotyping of nodal T-cell lymphomas reveals immune alterations and therapeutic targets
Stephan P, Perrot J, Voisin A, Barbery M, Andrieu T, Grimont M, Caramel J, Bardou M, Tondeur G, Missiaglia E, Gaulard P, Lemmonier F, De Leval L, Bachy E, Sujobert P, Genestier L, Traverse-Glehen A, Grinberg-Bleyer Y
Haematologica 2024
PMID: 38813724 - DOI: 10.3324/haematol.2023.284448
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4 A novel inhibitor of the mitochondrial respiratory complex I with uncoupling properties exerts potent antitumor activity
Al Assi A, Posty S, Lamarche F, Chebel A, Guitton J, Cottet-Rousselle C, Prudent R, Lafanechère L, Giraud S, Dallemagne P, Suzanne P, Verney A, Genestier L, Castets M, Fontaine E, Billaud M, Cordier-Bussat M
Cell Death Dis 2024 15(5): 311
PMID: 38697987 - DOI: 10.1038/s41419-024-06668-9
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5 Optogenetically controlled inflammasome activation demonstrates two phases of cell swelling during pyroptosis
Nadjar J, Monnier S, Bastien E, Huber AL, Oddou C, Bardoulet L, Leloup HB, Ichim G, Vanbelle C, Py BF, Destaing O, Petrilli V
Sci Signal 2024 17(833): eabn8003
PMID: 38652763 - DOI: 10.1126/scisignal.abn8003
Coauteur: VANBELLE Christophe (CyLE: Cytométrie Lyon-Est)
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6 Mitochondrial Ribosomal Protein MRPS15 Is a Component of Cytosolic Ribosomes and Regulates Translation in Stressed Cardiomyocytes
David F, Roussel E, Froment C, Draia-Nicolau T, Pujol F, Burlet-Schiltz O, Henras AK, Lacazette E, Morfoisse F, Tatin F, Diaz JJ, Catez F, Garmy-Susini B, Prats AC
Int J Mol Sci 2024 25(6)
PMID: 38542224 - DOI: 10.3390/ijms25063250
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7 The NF-?B RelA transcription factor is not required for CD8+ T-cell function in acute viral infection and cancer
Voisin A, Plaschka M, Perrin-Niquet M, Twardowski J, Boutemine I, Eluard B, Lalle G, Stéphan P, Bouherrou K, Tonon L, Pommier R, Ferrari A, Klein U, Wencker M, Baud V, Cassier PA, Grinberg-Bleyer Y
Front Immunol 2024 15: 1379777
PMID: 38504985 - DOI: 10.3389/fimmu.2024.1379777
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8 Spatial sequestration of activated-caspase 3 in aggresomes mediates resistance of neuroblastoma cell to bortezomib treatment
Berthenet K, Aïmontché E, El Mrini S, Brière J, Pion N, Iacono I, Brejon S, Monier K, Catez F, Ichim G, Combaret V, Mertani HC, Diaz JJ, Albaret MA
Sci Rep 2024 14(1): 3768
PMID: 38355966 - DOI: 10.1038/s41598-024-54140-7
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9 Cooperative pro-tumorigenic adaptation to oncogenic RAS through epithelial-to-mesenchymal plasticity
De Blander H, Tonon L, Fauvet F, Pommier RM, Lamblot C, Benhassoun R, Angileri F, Gibert B, Rodriguez R, Ouzounova M, Morel AP, Puisieux A
Sci Adv 2024 10(7): eadi1736
PMID: 38354248 - DOI: 10.1126/sciadv.adi1736
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10 Neonatal brain injury unravels transcriptional and signaling changes underlying the reactivation of cortical progenitors
Foucault L, Capeliez T, Angonin D, Lentini C, Bezin L, Heinrich C, Parras C, Donega V, Marcy G, Raineteau O
Cell Rep 2024 43(2): 113734
PMID: 38349790 - DOI: 10.1016/j.celrep.2024.113734
Remerciement: BATTISTON MONTAGNE Priscillia (CyLE: Cytométrie Lyon-Est)
Remerciement plateforme: CyLE: Cytométrie Lyon-Est
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11 Cholesterol biosynthetic pathway induces cellular senescence through ERR?
Ziegler DV, Czarnecka-Herok J, Vernier M, Scholtes C, Camprubi C, Huna A, Massemin A, Griveau A, Machon C, Guitton J, Rieusset J, Vigneron AM, Giguère V, Martin N, Bernard D
NPJ Aging 2024 10(1): 5
PMID: 38216569 - DOI: 10.1038/s41514-023-00128-y
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12 MDR1-EXPRESSING CD4+ T CELLS WITH TH1.17 FEATURES RESIST TO NEOADJUVANT CHEMOTHERAPY AND ARE ASSOCIATED WITH BREAST CANCER CLINICAL RESPONSE
Di Roio A, Hubert M, Besson L, Bossennec M, Rodriguez C, Grinberg-Bleyer Y, Lalle G, Moudombi L, Schneider R, Degletagne C, Treilleux I, Campbell DJ, Metzger S, Duhen T, Trédan O, Caux C, Ménétrier-Caux C
J Immunother Cancer 2023 11(11)
PMID: 37940345 - DOI: 10.1136/jitc-2023-007733
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13 Dill extract preserves dermal elastic fibers network and functionality. Implication of elafin
Aimond G, Nicolle S, Debret R, Oréa V, Josset-Lamaugarny A, Palierne JF, Sommer P, Sigaudo-Roussel D, Fromy B
Skin Pharmacol Physiol 2023
PMID: 37788642 - DOI: 10.1159/000534248
Remerciement: VANBELLE Christophe (CyLE: Cytométrie Lyon-Est)
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14 An Early Neoplasia Index (ENI10), Based on Molecular Identity of CD10 Cells and Associated Stemness Biomarkers, is a Predictor of Patient Outcome in Many Cancers
Guyot B, Clément F, Drouet Y, Schmidt X, Lefort S, Delay E, Treilleux I, Foy JP, Jeanpierre S, Thomas E, Kielbassa J, Tonon L, Zhu HH, Saintigny P, Gao WQ, de la Fouchardiere A, Tirode F, Viari A, Blay JY, Maguer-Satta V
Cancer Res Commun 2023 3(9): 1966-1980
PMID: 37707389 - DOI: 10.1158/2767-9764.CRC-23-0196
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15 Loss of Pla2r1 decreases cellular senescence and age-related alterations caused by aging and Western diets
Massemin A, Goehrig D, Flaman JM, Jaber S, Griveau A, Djebali S, Marcos E, Payen L, Marvel J, Parent R, Adnot S, Bertolino P, Rieusset J, Tortereau A, Vindrieux D, Bernard D
Aging Cell 2023 22(11): e13971
PMID: 37667516 - DOI: 10.1111/acel.13971
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16 Netrin-1 blockade inhibits tumor associated Myeloid-derived suppressor cells, cancer stemness and alleviates resistance to chemotherapy and immune checkpoint inhibitor
Ducarouge B, Redavid AR, Victoor C, Chira R, Fonseca A, Hervieu M, Bergé R, Lengrand J, Vieugué P, Neves D, Goddard I, Richaud M, Laval PA, Rama N, Goldschneider D, Paradisi A, Gourdin N, Chabaud S, Treilleux I, Gadot N, Ray-Coquard I, Depil S, Decaudin D
Cell Death Differ 2023 30(10): 2201-2212
PMID: 37633969 - DOI: 10.1038/s41418-023-01209-x
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17 Netrin-1 blockade inhibits tumor associated Myeloid-derived suppressor cells, cancer stemness and alleviates resistance to chemotherapy and immune checkpoint inhibitor
Ducarouge B, Redavid AR, Victoor C, Chira R, Fonseca A, Hervieu M, Bergé R, Lengrand J, Vieugué P, Neves D, Goddard I, Richaud M, Laval PA, Rama N, Goldschneider D, Paradisi A, Gourdin N, Chabaud S, Treilleux I, Gadot N, Ray-Coquard I, Depil S, Decaudin D
Cell Death Differ 2023 30(10): 2201-2212
PMID: 37633969 - DOI: 10.1038/s41418-023-01209-x
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18 Characterization of the Zebrafish Elastin a (elnasa12235) Mutant: A New Model of Elastinopathy Leading to Heart Valve Defects
Hoareau M, El Kholti N, Debret R, Lambert E
Cells 2023 12(10)
PMID: 37408270 - DOI: 10.3390/cells12101436
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19 Single-cell analysis of the postnatal dorsal V-SVZ reveals a role for Bmpr1a signaling in silencing pallial germinal activity
Marcy G, Foucault L, Babina E, Capeliez T, Texeraud E, Zweifel S, Heinrich C, Hernandez-Vargas H, Parras C, Jabaudon D, Raineteau O
Sci Adv 2023 9(18): eabq7553
PMID: 37146152 - DOI: 10.1126/sciadv.abq7553
Remerciement: BATTISTON MONTAGNE Priscillia (CyLE: Cytométrie Lyon-Est)
Remerciement plateforme: CyLE: Cytométrie Lyon-Est
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20 Analysis of biomechanical properties of mouse skin dermis through atomic force microscopy: Application to demonstrate a sexual dimorphism
Prigent L, Mercier-Gouy P, Bovio S, Aubert A, Liot S, Lambert E, Valcourt U
Exp Dermatol 2023 32(7): 1016-1027
PMID: 37029962 - DOI: 10.1111/exd.14807
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21 RSL24D1 sustains steady-state ribosome biogenesis and pluripotency translational programs in embryonic stem cells
Durand S, Bruelle M, Bourdelais F, Bennychen B, Blin-Gonthier J, Isaac C, Huyghe A, Martel S, Seyve A, Vanbelle C, Adrait A, Couté Y, Meyronet D, Catez F, Diaz JJ, Lavial F, Ricci EP, Ducray F, Gabut M
Nat Commun 2023 14(1): 356
PMID: 36690642 - DOI: 10.1038/s41467-023-36037-7
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22 A Human Bone Marrow 3D Model to Investigate the Dynamics and Interactions Between Resident Cells in Physiological or Tumoral Contexts
Arizkane K, Geistlich K, Moindrot L, Risson E, Jeanpierre S, Barral L, Bobard A, Menegazzi G, Voeltzel T, Maguer-Satta V, Lefort S
J Vis Exp 2022 (190)
PMID: 36591983 - DOI: 10.3791/64736
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23 Mass cytometry analysis reveals attrition of naïve and anergized self-reactive non-malignant B cells in chronic lymphocytic leukemia patients
Andrieu T, Mondière P, Jouve PE, Dussurgey S, Malassigné V, Servanton H, Baseggio L, Davi F, Michallet AS, Defrance T
Front Oncol 2022 12: 1020740
PMID: 36387187 - DOI: 10.3389/fonc.2022.1020740
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24 SMAD2/3 mediate oncogenic effects of TGF-? in the absence of SMAD4
Bertrand-Chapel A, Caligaris C, Fenouil T, Savary C, Aires S, Martel S, Huchedé P, Chassot C, Chauvet V, Cardot-Ruffino V, Morel AP, Subtil F, Mohkam K, Mabrut JY, Tonon L, Viari A, Cassier P, Hervieu V, Castets M, Mauviel A, Sentis S, Bartholin L
Commun Biol 2022 5(1): 1068
PMID: 36207615 - DOI: 10.1038/s42003-022-03994-6
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25 Comparative roadmaps of reprogramming and oncogenic transformation identify Bcl11b and Atoh8 as broad regulators of cellular plasticity
Huyghe A, Furlan G, Schroeder J, Cascales E, Trajkova A, Ruel M, Stüder F, Larcombe M, Yang Sun YB, Mugnier F, De Matteo L, Baygin A, Wang J, Yu Y, Rama N, Gibert B, Kielbassa J, Tonon L, Wajda P, Gadot N, Brevet M, Siouda M, Mulligan P, Dante R, Liu P, G
Nat Cell Biol 2022 24(9): 1350-1363
PMID: 36075976 - DOI: 10.1038/s41556-022-00986-w
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26 Common and Exclusive Features of Intestinal Intraepithelial ?? T Cells and Other ?? T Cell Subsets
Apostolov AK, Hamani M, Hernandez-Vargas H, Igalouzene R, Guyennon A, Fesneau O, Marie JC, Soudja SM
Immunohorizons 2022 6(7): 515-527
PMID: 35878935 - DOI: 10.4049/immunohorizons.2200046
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27 In Vivo Syngeneic Tumor Models with Acquired Resistance to Anti-PD-1/PD-L1 Therapies
Denis M, Grasselly C, Choffour PA, Wierinckx A, Mathé D, Chettab K, Tourette A, Talhi N, Bourguignon A, Birzele F, Kress E, Jordheim LP, Klein C, Matera EL, Dumontet C
Cancer Immunol Res 2022 10(8): 1013-1027
PMID: 35679518 - DOI: 10.1158/2326-6066.CIR-21-0802
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28 SMAD4 TGF-?-independent function preconditions naive CD8+ T cells to prevent severe chronic intestinal inflammation
Igalouzene R, Hernandez-Vargas H, Benech N, Guyennon A, Bauché D, Barrachina C, Dubois E, Marie JC, Soudja SM
J Clin Invest 2022 132(8)
PMID: 35426367 - DOI: 10.1172/JCI151020
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29 In-Depth Immunophenotyping With Mass Cytometry During TB Treatment Reveals New T-Cell Subsets Associated With Culture Conversion
Chedid C, Andrieu T, Kokhreidze E, Tukvadze N, Biswas S, Ather MF, Uddin MKM, Banu S, De Maio F, Delogu G, Endtz H, Goletti D, Vocanson M, Dumitrescu O, Hoffmann J, Ader F
Front Immunol 2022 13: 853572
PMID: 35392094 - DOI: 10.3389/fimmu.2022.853572
Coauteur: ANDRIEU Thibault (CyLE: Cytométrie Lyon-Est)
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30 ZEB1 transcription factor promotes immune escape in melanoma
Plaschka M, Benboubker V, Grimont M, Berthet J, Tonon L, Lopez J, Le-Bouar M, Balme B, Tondeur G, de la Fouchardière A, Larue L, Puisieux A, Grinberg-Bleyer Y, Bendriss-Vermare N, Dubois B, Caux C, Dalle S, Caramel J
J Immunother Cancer 2022 10(3)
PMID: 35288462 - DOI: 10.1136/jitc-2021-003484
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31 Hepatic inflammation elicits production of proinflammatory netrin-1 through exclusive activation of translation
Barnault R, Verzeroli C, Fournier C, Michelet M, Redavid AR, Chicherova I, Plissonnier ML, Adrait A, Khomich O, Chapus F, Richaud M, Hervieu M, Reiterer V, Centonze FG, Lucifora J, Bartosch B, Rivoire M, Farhan H, Couté Y, Mirakaj V, Decaens T, Mehlen P,
Hepatology 2022 76(5): 1345-1359
PMID: 35253915 - DOI: 10.1002/hep.32446
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32 Identification of shared tumor epitopes from endogenous retroviruses inducing high-avidity cytotoxic T cells for cancer immunotherapy
Bonaventura P, Alcazer V, Mutez V, Tonon L, Martin J, Chuvin N, Michel E, Boulos RE, Estornes Y, Valladeau-Guilemond J, Viari A, Wang Q, Caux C, Depil S
Sci Adv 2022 8(4): eabj3671
PMID: 35080970 - DOI: 10.1126/sciadv.abj3671
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33 A minimal standardized human bone marrow microphysiological system to assess resident cell behavior during normal and pathological processes
Voeltzel T, Fossard G, Degaud M, Geistlich K, Gadot N, Jeanpierre S, Mikaelian I, Brevet M, Anginot A, Le Bousse-Kerdilès MC, Trichet V, Lefort S, Maguer-Satta V
Biomater Sci 2022 10(2): 485-498
PMID: 34904143 - DOI: 10.1039/d1bm01098k
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34 H3.3K27M Mutation Controls Cell Growth and Resistance to Therapies in Pediatric Glioma Cell Lines
Rakotomalala A, Bailleul Q, Savary C, Arcicasa M, Hamadou M, Huchedé P, Hochart A, Restouin A, Castellano R, Collette Y, Dieny E, Vincent A, Angrand PO, Le Bourhis X, Leblond P, Furlan A, Castets M, Pasquier E, Meignan S
Cancers (Basel) 2021 13(21)
PMID: 34771714 - DOI: 10.3390/cancers13215551
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35 Regulatory T cells promote cancer immune-escape through integrin ?v?8-mediated TGF-? activation
Lainé A, Labiad O, Hernandez-Vargas H, This S, Sanlaville A, Léon S, Dalle S, Sheppard D, Travis MA, Paidassi H, Marie JC
Nat Commun 2021 12(1): 6228
PMID: 34711823 - DOI: 10.1038/s41467-021-26352-2
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36 Immunogenicity and efficacy of ?????????heterologous ChAdOx1-BNT162b2 vaccination
Pozzetto B, Legros V, Djebali S, Barateau V, Guibert N, Villard M, Peyrot L, Allatif O, Fassier JB, Massardier-Pilonchéry A, Brengel-Pesce K, Yaugel-Novoa M, Denolly S, Boson B, Bourlet T, Bal A, Valette M, Andrieu T, Lina B, Cosset FL, Paul S, Defrance T
Nature 2021 600(7890): 701-706
PMID: 34673755 - DOI: 10.1038/s41586-021-04120-y
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37 A T cell-intrinsic function for NF-?B RelB in experimental autoimmune encephalomyelitis
Lalle G, Lautraite R, Voisin A, Twardowski J, Stéphan P, Perrin-Niquet M, Igalouzene R, Soudja SM, Marie JC, Vocanson M, De Silva N, Klein U, Ghosh S, Grinberg-Bleyer Y
Sci Rep 2021 11(1): 19674
PMID: 34608221 - DOI: 10.1038/s41598-021-99134-x
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38 Development of thymic tumor in [LSL:KrasG12D; Pdx1-CRE] mice, an adverse effect associated with accelerated pancreatic carcinogenesis
Liot S, El Kholti N, Balas J, Genestier L, Verrier B, Valcourt U, Lambert E
Sci Rep 2021 11(1): 15075
PMID: 34302028 - DOI: 10.1038/s41598-021-94566-x
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39 Caspase-8 deficiency induces a switch from TLR3 induced apoptosis to lysosomal cell death in neuroblastoma
Locquet MA, Ichim G, Bisaccia J, Dutour A, Lebecque S, Castets M, Weber K
Sci Rep 2021 11(1): 10609
PMID: 34011952 - DOI: 10.1038/s41598-021-89793-1
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40 Calcium channel ITPR2 and mitochondria-ER contacts promote cellular senescence and aging
Ziegler DV, Vindrieux D, Goehrig D, Jaber S, Collin G, Griveau A, Wiel C, Bendridi N, Djebali S, Farfariello V, Prevarskaya N, Payen L, Marvel J, Aubert S, Flaman JM, Rieusset J, Martin N, Bernard D
Nat Commun 2021 12(1): 720
PMID: 33526781 - DOI: 10.1038/s41467-021-20993-z
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41 CD73 and cN-II regulate the cellular response to chemotherapeutic and hypoxic stress in lung adenocarcinoma cells
Raza MZ, Cadassou O, Dumontet C, Cros-Perrial E, Jordheim LP
Biochim Biophys Acta Gen Subj 2021 1865(5): 129842
PMID: 33434633 - DOI: 10.1016/j.bbagen.2021.129842
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42 A new agarose-based microsystem to investigate cell response to prolonged confinement
Prunet A, Lefort S, Delanoë-Ayari H, Laperrousaz B, Simon G, Barentin C, Saci S, Argoul F, Guyot B, Rieu JP, Gobert S, Maguer-Satta V, Rivière C
Lab Chip 2020 20(21): 4016-4030
PMID: 32975276 - DOI: 10.1039/d0lc00732c
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43 Failed Apoptosis Enhances Melanoma Cancer Cell Aggressiveness
Berthenet K, Castillo Ferrer C, Fanfone D, Popgeorgiev N, Neves D, Bertolino P, Gibert B, Hernandez-Vargas H, Ichim G
Cell Rep 2020 31(10): 107731
PMID: 32521256 - DOI: 10.1016/j.celrep.2020.107731
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44 ERR? Expression in Bone Metastases Leads to an Exacerbated Antitumor Immune Response
Bouchet M, Lainé A, Boyault C, Proponnet-Guerault M, Meugnier E, Bouazza L, Kan CWS, Geraci S, El-Moghrabi S, Hernandez-Vargas H, Benetollo C, Yoshiko Y, Duterque-Coquillaud M, Clézardin P, Marie JC, Bonnelye E
Cancer Res 2020 80(13): 2914-2926
PMID: 32366476 - DOI: 10.1158/0008-5472.CAN-19-3584
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45 IFN-III is selectively produced by cDC1 and predicts good clinical outcome in breast cancer
Hubert M, Gobbini E, Couillault C, Manh TV, Doffin AC, Berthet J, Rodriguez C, Ollion V, Kielbassa J, Sajous C, Treilleux I, Tredan O, Dubois B, Dalod M, Bendriss-Vermare N, Caux C, Valladeau-Guilemond J
Sci Immunol 2020 5(46)
PMID: 32303573 - DOI: 10.1126/sciimmunol.aav3942
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46 Netrin-1 promotes naive pluripotency through Neo1 and Unc5b co-regulation of Wnt and MAPK signalling
Huyghe A, Furlan G, Ozmadenci D, Galonska C, Charlton J, Gaume X, Combémorel N, Riemenschneider C, Allègre N, Zhang J, Wajda P, Rama N, Vieugué P, Durand I, Brevet M, Gadot N, Imhof T, Merrill BJ, Koch M, Mehlen P, Chazaud C, Meissner A, Lavial F
Nat Cell Biol 2020 22(4): 389-400
PMID: 32231305 - DOI: 10.1038/s41556-020-0483-2
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47 The quiescent fraction of chronic myeloid leukemic stem cells depends on BMPR1B, Stat3 and BMP4-niche signals to persist in patients in remission
Jeanpierre S, Arizkane K, Thongjuea S, Grockowiak E, Geistlich K, Barral L, Voeltzel T, Guillemin A, Gonin-Giraud S, Gandrillon O, Nicolini FE, Mead AJ, Maguer-Satta V, Lefort S
Haematologica 2021 106(1): 111-122
PMID: 32001529 - DOI: 10.3324/haematol.2019.232793
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48 Transforming Growth Factor-beta signaling in ?? thymocytes promotes negative selection
McCarron MJ, Irla M, Sergé A, Soudja SM, Marie JC
Nat Commun 2019 10(1): 5690
PMID: 31857584 - DOI: 10.1038/s41467-019-13456-z
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49 Methotrexate Restores CD73 Expression on Th1.17 in Rheumatoid Arthritis and Psoriatic Arthritis Patients and May Contribute to Its Anti-Inflammatory Effect through Ado Production
Bossennec M, Rodriguez C, Hubert M, Di-Roio A, Machon C, Guitton J, Battiston-Montagne P, Couturier M, Marotte H, Caux C, Coury F, Ménétrier-Caux C
J Clin Med 2019 8(11)
PMID: 31684171 - DOI: 10.3390/jcm8111859
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50 Repurposing rotavirus vaccines for intratumoral immunotherapy can overcome resistance to immune checkpoint blockade
Shekarian T, Sivado E, Jallas AC, Depil S, Kielbassa J, Janoueix-Lerosey I, Hutter G, Goutagny N, Bergeron C, Viari A, Valsesia-Wittmann S, Caux C, Marabelle A
Sci Transl Med 2019 11(515)
PMID: 31645452 - DOI: 10.1126/scitranslmed.aat5025
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51 Release of c-FLIP brake selectively sensitizes human cancer cells to TLR3-mediated apoptosis
Alkurdi L, Virard F, Vanbervliet B, Weber K, Toscano F, Bonnin M, Le Stang N, Lantuejoul S, Micheau O, Renno T, Lebecque S, Estornes Y
Cell Death Dis 2018 9(9): 874
PMID: 30158588 - DOI: 10.1038/s41419-018-0850-0
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52 Synthesis and antitumor activity of a new class of pyrazolo[4,3-e]pyrrolo[1,2-a][1,4]diazepinone analogues of pyrrolo[1,4][2,1-c]benzodiazepines
Baraldi PG, Leoni A, Cacciari B, Manfredini S, Simoni D, Bergomi M, Menta E, Spinelli S
J Med Chem 1994 37(25): 4329-37
PMID: 7996544 - DOI: 10.1021/jm00051a009
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Afficher les 52 articles dans PubMedExporter les 52 articles depuis PubMed: medline abstract uilist
Dernière MAJ bibliographie: Lundi 2 Septembre 2024